A Framework for Analysis of SNPs in TAGAP Gene

Authors

  • Haider Usman Department of Computer Science, Bahauddin Zakariya University, Multan,60000, Pakistan
  • Qaisar Rasool Department of Computer Science, Bahauddin Zakariya University, Multan, 60000, Pakistan
  • Saad Rasool Department of Computer Science, Bahauddin Zakariya University, Multan, 60000, Pakistan
  • Hifssa Aslam Department of Computer Science, Bahauddin Zakariya University, Multan, 60000, Pakistan

Keywords:

TAGAP, T cells, Single Nucleotide, Non synonymous SNPs (nsSNPs), Protein structure, Protein functionality

Abstract

The role of TAGAP in the T cells plays a vital role and the analysis of how the structure and functional impact SNPs have on the TAGAP is the main focus that has been analyzed within the provided studies. Analysis of the genetic maps that are developed within the human body has been analyzed with testing the impact of the mutation on the TAPAG in T cells. The examination of non-synonymous Single Nucleotide Polymorphisms (nsSNPs) on the TAGAP gene functionality and structural characteristics. Four tests have been performed are SIFT, Polyphen-2, PROVEAN, and the stability of the protein was tested through the I-Mutants 3.0. Diabetes Mellitus and Auditory Agnosia are the two diseases that have been analyzed to depict the importance of the TAGAP in the T cells.

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Published

2024-03-14

How to Cite

Usman, H., Rasool, Q., Rasool, S., & Aslam, H. (2024). A Framework for Analysis of SNPs in TAGAP Gene. Machines and Algorithms, 3(1), 43–60. Retrieved from https://knovell.org/MnA/index.php/ojs/article/view/60

Issue

Vol. 3 No. 1 (2024): Regular Issue

Section

Articles

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